In the fourth and last Red Ryder (following "Ride, Rider, Ride", "Roll, Thunder, Roll" and "The Fighting Redhead" in that order) of the Equity Pictures for Eagle-Lion distribution, filmed in Cinecolor, Red Ryder takes Steve Stevenson, who has saved Red's life, to his ranch and gives him a job. Red's aunt, the Duchess, knew Steve's father, who supposedly committed suicide after losing his ranch betting on a prizefight. Steve refuses to believe that his father took his own life and the Duchess backs him up. On the way to town, Red, Steve, ranch hand Buckshot Blodgett and Red's young Indian pal, Little Beaver, break up an attempted stagecoach robbery. Mark Palmer, the gambler who caused the death of Steve's father, is a passenger. In town, Steve meets Sue Evans, who is going to work for saloon owner Bart Osborne. Palmer and Osborne are working together and want Ryder's ranch, and they develop a plan to have Red fight Palmer's pugilist, Bull Massoon. Steve, a boxer in college, takes Red's place. Steve loses to Massoon, but before Red can determine whether it was a fair fight, a rider reports a robbery of the stage office. Red goes after the outlaws, and the gold is recovered. Red maneuvers a fight with Massoon, and beats him after Massoon drops a piece of lead pipe hidden in his hand. Palmer admits to having murdered Steve's father, and Steve learns that Sue was forced to work for Osborne to pay off a debt owed by her brother.

Dr. Allen Seward (Robert Francis) is assigned to a western cavalry post where his predecessors had been drunks and slackers. The post doesn't take kindly to him either, especially after he disregards regulations and tends to sick Indians on the malaria-infested reservation. The Indians break away from the reservation to move to a healthier higher ground, and when they join with the Comanches to besiege the fort, Seward is branded as a "woodhawk", the bird that turns against its own. Donna Reed is present as the niece of the post commander; Phil Carey is a cavalry captain that believes the only good Indian is a dead Indian, and May Wynn (who shared a screen debut with Francis in "The Caine Mutiny)is the white girl raised by the Indians and married to the chief's son. Francis would make only two more films before being killed in a 1955 plane crash.

Having eluded a posse, a wanted man rescues a woman and her young son from a Comanche attack. He then escorts them to the presumed safety of a U.S. Cavalry fort. Trouble develops along the way when the woman comes to believe that her rescuer was responsible for the recent death of her husband.

In Oregon Country, 1868, several tribes of Native Americans have been placed on a reservation north of the Snake River. Here Doctor Holden has built a church, and many of the tribes have accepted Christianity and Christian names. Sgt. Emmett Bell is in charge of maintaining order here. When the cavalry, under the command of Col. Stedlow, arrives, building a bridge across the river and intending to open a road across the reservation to areas north, some of the tribal chiefs feel their treaty has been violated. As the cavalry column advances into the reservation, Kamiakin vows to lead the tribes in battle against the encroaching white men.

A stranger being chased by bandits dies in an accident, but not before he has had a chance to hide a treasure map the bandits wanted. A boy witnesses where it was hidden, retrieves it and passes it on to the local preacher. The preacher recognizes that much of the treasure was likely that from a local mission. He sets out to get it before the bandits find it.

Robber Roy King loses his wife, Alicia, to revolutionary Montero. Despite their rivalry they collaborate in an attempt to rob the Mexican government of one million dollars

Tenderfoot Burton and his wife join forces with an old prospector to search for the rich gold strike the old-timer claims to know of. Along with a couple of no-account gunslingers, they ride deep into the mountains to find the gold, unaware that the treasure is guarded by an all-female tribe of deadly, beautiful, and topless Indians.

Joe Baker has a dream. He wants to do 'something big.' When he needs a Gatling gun to accomplish this, he seeks out a black marketeer. The price he wants for the gun? A woman! So Baker kidnaps a woman off of the stagecoach, only to find that she is the wife of the commandant of the local Cavalry detachment. Things get further complicated when a girl named Dover McBride shows up. She has come to force Baker to marry her and return east, as he promised to do four years earlier.

The Crazy Gang join the 1898 gold rush. Unfortunately it's now 1939 and they're a bit late.

Rodeo star Roy Rogers (Roy Rogers), returning with his horse "Trigger" to his home town, finds old Tom Craig (Leyland Hodgson) murdered and offers his aid to "acting sheriff" Gabby Whittaker (George Hayes). Roy meets Helen Williams (Dale Evans), new singer at the Trading Post club, who is on her way to see Craig about a family-heirloom crest which he has stolen from her father. Arthur Courtney (Douglass Dumbrille)is informed by his henchmen that Craig is dead but they were unable to find the crest since Gabby, Helen and Roy had appeared on the scene. He orders them to get rid of Roy and Helen. After narrowly missing being killed while on their way to an Indian pow-wow, Roy and Gabby go to the Craig ranch where they discover an old clock and the crest hidden it it. They are taken captive by Courtney's henchmen and watch Courtney press a catch on the crest and take out a piece of paper. A fight ensues and The Sons of the Pioneers (Bob Nolan, Tim Spencer, Hugh Farr, Karl Farr and "Shug" Fisher) and Roy's Indian friends come to Roy's and Gabby's aid.