The Simpsons is an animated sitcom about the antics of a dysfunctional family called the Simpsons (surprise surprise). Homer is the oafish unhealthy beer loving father, Marge is the hardworking homemaker wife, Bart is the ten year old underachiever (and proud of it), Lisa is the unappreciated eight year old genius, and Maggie is the cute, pacifier loving silent infant.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle gets permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes. A "guy's guy", he proves popular with the male team members, but immediately offends the sensibilities of the team leader, Detective Kate Beckett. Though she'll never admit it, he slowly wins her over with his innovative approach to crime solving. He brings to the table skills the others don't have: contacts in Manhattan high society, free-form creative thinking, and years of developing believable fictional characters that have inadvertently molded him into a natural criminal profiler. But life is not all crime fighting adventure for this wealthy playboy: his relationship with Beckett becomes even more strained when he unveils a new series of detective novels featuring a racy character based on her, and his home life is dominated by his mother (a fading Broadway diva) and his whip-smart teen-aged daughter.

Grey's Anatomy is a medical drama set at the fictional Seattle Grace Mercy West Hospital in Seattle. The series covers the stories of the interns and residents at the hospital as they try to balance their personal lives with the demands of their medical training. The main character is Meredith Grey, who is married to a neurosurgeon at the hospital .The show follows her life as a third year resident at the hospital in the surgical department run by Dr Richard Webber. It covers not only her relationship with her husband, but also with her best friend Cristina Yang and her interactions with the other doctors and staff.

After saving the life of the President in Washington D.C., a pair of U.S Secret Service agents are whisked away to a covert location in South Dakota that houses supernatural objects that the Regents, an Authority above and outside any government, have collected over the centuries. Their new assignment: retrieve any lost objects and investigate reports of new ones.

The Harper brothers Charlie and Alan are almost opposites but form a great team. They have little in common except their dislike for their mundane, maternally cold and domineering mother, Evelyn. Alan, a compulsively neat chiropractor and control-freak, is thrown out by his manipulative wife Judith who nevertheless gets him to pay for everything and do most jobs in the house. Charlie is a freelance jingle composer and irresistible Cassanova who lives in a luxurious beach-house and rarely gets up before noon. Charlie "temporarily" allows Alan and his son Jake, a food-obsessed, lazy school kid who shuttles between his parents, to move in with them after Alan's separation/divorce. The sitcom revolves around their conflicting lifestyles, raising Jake (who has the efficient, caring dad while having a ball with his fun-loving sugar uncle who teaches him boyish things), and bantering with Evelyn and various other friends and family. Other fairly regular characters include Charlie's cleaning lady Berta and his rich, self-confessed stalker neighbor Rose who often sneaks in to spy on Charlie.

The absurd antics of an Indiana town's public officials as they pursue sundry projects to make their city a better place.