A modern take on the cases of Sherlock Holmes, with the detective now living in New York City.

After saving the life of the President in Washington D.C., a pair of U.S Secret Service agents are whisked away to a covert location in South Dakota that houses supernatural objects that the Regents, an Authority above and outside any government, have collected over the centuries. Their new assignment: retrieve any lost objects and investigate reports of new ones.

Hawaii doesn't have its own state police force but the Governor has set up a special task force, which becomes known as "Five-0", to investigate serious crimes on the islands. Reserve Naval officer Steve McGarrett heads the team with Danny Williams as his second in command and together they tackle a range of crimes with more far-reaching consequences than those dealt with by HPD, including terrorism and serious organized crime.

Emily Taylor, despite being reunited with her husband from prison, becomes severely depressed with emotional episodes and suicide attempts. Her psychiatrist, Jonathan Banks, after conferring with her previous doctor, eventually prescribes an experimental new medication called Ablixa. The plot thickens when the side effects of the drug lead to Emily killing her husband in a "sleepwalking" state. With Emily plea-bargained into mental hospital confinement and Dr. Banks' practice crumbling around him, the case seems closed. However, Dr. Banks cannot accept full responsibility and investigates to clear his name. What follows is a dark quest that threatens to tear what's left of his life apart even as he discovers the diabolical truth of this tragedy.

When an unseen enemy threatens mankind by taking over their bodies and erasing their memories, Melanie will risk everything to protect the people she cares most about, proving that love can conquer all in a dangerous new world.

When the crew of the Enterprise is called back home, they find an unstoppable force of terror from within their own organization has detonated the fleet and everything it stands for, leaving our world in a state of crisis. With a personal score to settle, Captain Kirk leads a manhunt to a war-zone world to capture a one man weapon of mass destruction. As our heroes are propelled into an epic chess game of life and death, love will be challenged, friendships will be torn apart, and sacrifices must be made for the only family Kirk has left: his crew.