The story is set in both Hong Kong and the U.S. So goes to the U.S. to open a martial arts school. Around this time, many Chinese people were sold off to U.S. railroad companies, and were brutally treated by the Americans under the harsh working conditions. Thus, the American workers' hatred towards the Chinese immigrants is high. As a result, So gets into trouble with the Americans and the mob, and calls Master Wong for help.

Thanks to a treacherous employee, South African White supremacists storm a UN facility specializing in germ warfare and treatment. They reward their traitor by disposing of him along with everyone else inside bar one. Major Tipton who just arrived to pick up vials of a newly discovered lethal strain of Ebola virus along with it's cure...not only manages to evade their strike but manages to kill one or two members of the hit squad before destroying their chopper and pilots along with it. Undaunted by this setback the surviving extremists set out to hijack a train back to their base...now in possession of the very same virus together with its antidote Tipton was meant to collect. Delta force operatives, led by Captain Lang are dispatched to retrieve the vials along with south African military officer Lt. Marie Yonker, an expert on African Righ-Wing groups like the ones they are now after. Depite his needed skills in diseases Tipton is far from welcomed into aiding the team in it's pursuit due to letting the brother of Lang die in a mission some time ago. All the while the supremacists are getting further away from operation delta force